Jim Shaw
Hi there! I am an NSERC Postdoctoral Fellow at Harvard Medical School and Dana-Farber Cancer Institute. I work with Heng Li. You can reach me at jshaw(at)ds.dfci.harvard.edu.
I obtained my PhD in Math at the University of Toronto, where I was advised by Yun William Yu. Previously, I studied Engineering Physics + Mathematics at the University of British Columbia.
Research interests
I develop algorithms/software/theory for biological sequence analysis and apply these methods to investigate important problems in microbial and microbiome genomics.
More specifically, two intertwined themes define my current work:
- Building sophisticated bioinformatics tools to improve the analysis of massive microbial and meta-omics data.
- Obtaining new insights about microbiome genome evolution through principled analytical methods.
For example, see my work on ultrafast microbial divergence computation, rapid metagenome profiling, and long-read metagenome assembly. When I have the chance, I also enjoy doing a bit of theory.
news
| May 26, 2026 | Our new long-read amplicon sequence variant (ASV) generation method, savont, is now uploaded to bioRxiv. |
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| Mar 27, 2026 | Our long-read metagenome assembler, myloasm, is now published in Nature Biotechnology. |
| Sep 07, 2025 | Preprint for our new long-read metagenome assembler, myloasm, is out! |